Scientific perspectives

Rigorous Perspectives on Endocrine Science and Clinical Development

Independent analysis of emerging science, therapeutics, and clinical research across endocrinology and metabolic medicine.

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OBESITY · CLINICAL RESEARCH

Placebo Hygiene in the GLP-1 Era: When Placebo Participants Find Active Treatment

Clayton A. DehnOriginally published by Evolution Research Group

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BIOMARKERS · CARDIOMETABOLIC RESEARCH

When the Biomarker Moves but the Outcome Doesn't: What ZEUS Really Tells Us About Inflammation

Clayton A. DehnOriginally published by Evolution Research Group

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Pharmacodynamic Models for Predicting Weight Loss Efficacy in Early-Phase Trials

Dehn CA et al.Originally published by ERG/Lotus Clinical Research

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Focused Coverage Across Endocrine and Metabolic Science

Endocrinology

Hormonal regulation, endocrine disorders, and pathophysiology

Metabolism

Metabolic disease, energy homeostasis, and cardiometabolic risk

Obesity

Obesity biology, pharmacotherapy, and clinical development

Therapeutics

Drug mechanisms, clinical pharmacology, and treatment evidence

Clinical Research

Trial design, endpoints, biomarkers, and evidence generation

Drug Development

Translational research, regulatory science, and development strategy

Our mission

Independent Perspectives for the Scientific Community

Endocrine Insights provides rigorous, evidence-based commentary and analysis for researchers, clinicians, and clinical development professionals working across endocrinology, metabolism, and related therapeutic areas.

Our editorial focus is on interpreting complex and emerging science in context and examining its implications for clinical research, therapeutic development, and clinical understanding.

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